Activation of the platelets with TRAP-6 (which stimulates PAR-1) and the PMNs with C5a (which stimulates the C5a receptor and up-regulates surface CD11b) triggered formation
Activation of the platelets with TRAP-6 (which stimulates PAR-1) and the PMNs with C5a (which stimulates the C5a receptor and up-regulates surface CD11b) triggered formation